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Asymmetric, Organocatalytic Bromolactonization of Allenoic Acids

  • December 1, 2014

Asymmetric, reagent-controlled bromolactonizations of allenoic acids have been achieved by using (DHQD)2PHAL as catalyst. A range of substrates can be cyclized in good yields and moderate to good enantioselectivities under operationally simple conditions.

 

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