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Excess Electron Transport through DNA: a Single Electron Repairs More Than One UV-Induced Lesion

  • March 24, 2004

Site‐selective injection of a single electron into thymine (yellow) through the modified nucleoside 1(1→2) was used to examine the dependence of excess electron transfer in DNA on distance. The DNA was cleaved upon arrival of the electron at a thymine dimer (red). This assay showed that one electron can repair more than one UV‐induced lesion in DNA 3.

 

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