Blood-Brain barrier penetration by two dermorphin tetrapeptide analogues: Role of lipophilicity vs structural flexibility.
Ballet, S.; Misicka, A.; Kosson, P.; Lemieux, C.; Chung, N. N.; Schiller, P. W.; Lipkowski, A. W.; Tourwe, D., J. Med. Chem. 2008, 51, 2571-2574.
Read more
Endomorphin-2 with a beta turn backbone constraint retains the potent mu-opioid receptor agonist properties.
Tomboly, C.; Ballet, S.; Feytens, D.; Kover, K. E.; Borics, A.; Lovas, S.; Al-Khrasani, M.; Furst, Z.; Toth, G.; Benyhe, S.; Tourwe, D., J. Med. Chem. 2008, 51, 173-177.
Read more
Multiple Ligands in Opioid Research.
Ballet, S.; Pietsch, M.; Abell, A. D., Protein Pep. Lett. 2008, 15, 668-682.
Read more
A General Route to 4-C-Substituted Pyrimidine Nucleosides
U. Hennecke, D. Kuch, T. Carell, Synthesis 2007, 929-935.
Read more
High-performance liquid chromatographic separation of stereoisomers of N-phthaloyl-protected amino acids and dipeptidomimetics.
Illisz, I.; Ballet, S.; Van Rompaey, K.; De Wachter, R.; Tourwe, D.; Armstrong, D. W.; Peter, A., J. Sep. Sci. 2007, 30, 1881-1887.
Read more
Novel Selective human melanocortin-3 receptor ligands : Use of the 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-one (Aba) scaffold.
Ballet, S.; Mayorov, A. V.; Cai, M. Y.; Tymecka, D.; Chandler, K. B.; Palmer, E. S.; Van Rompaey, K.; Misicka, A.; Tourwe, D.; Hruby, V. J., Bioorg. Med. Chem. Lett. 2007, 17, 2492-2498.
Read more
Derivatization of 1-phenyl substituted 4-amino-2benzazepin-3-ones : evaluation of Pd-catalyzed coupling reactions.
Ballet, S.; De Wachter, R.; Maes, B. U. W.; Tourwe, D., Tetrahedron 2007, 63, 3718-3727.
Read more
CPD Damage Recognition by Transcribing RNA Polymerase II
F. Brückner, U. Hennecke, T. Carell, P. Cramer, Science 2007, 315, 859-862.
Read more
Bradykinin analogs containing the 4-amino-2-benzazepin-3-one scaffold at the C-terminus.
Ballet, S.; De Wachter, R.; Van Rompaey, K.; Tömböly, C.; Feytens, D.; Töth, G.; Quartara, L.; Cucchi, P.; Meini, S.; Tourwé, D., J. Pept. Sci. 2007, 13, 164-170.
Read more
beta-Methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists.
Toth, G.; Ioja, E.; Tomboly, C.; Ballet, S.; Tourwe, D.; Peter, A.; Martinek, T.; Chung, N. N.; Schiller, P. W.; Benyhe, S.; Borsodi, A., J. Med. Chem. 2007, 50, 328-333.
Read more
Characterization of a New Thermophilic Spore Photoproduct Lyase from Geobacillus stearothermophilus (SplG) with Defined Lesion Containing DNA Substrates
J. C. Pieck, U. Hennecke, A. J. Pierik, M. G. Friedel, T. Carell, J. Biol. Chem. 2006, 281, 36317-36326.
Read more
Natural and Non-Natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus
T. Klar, G. Kaiser, U. Hennecke, T. Carell, A. Batschauer, L.-O. Essen, ChemBioChem 2006, 7, 1798-1806.
Read more