News

Bradykinin analogs containing the 4-amino-2-benzazepin-3-one scaffold at the C-terminus.

Wednesday 31/01/2007

Ballet, S.; De Wachter, R.; Van Rompaey, K.; Tömböly, C.; Feytens, D.; Töth, G.; Quartara, L.; Cucchi, P.; Meini, S.; Tourwé, D., J. Pept. Sci. 2007, 13, 164-170.

beta-Methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists.

Monday 01/01/2007

Toth, G.; Ioja, E.; Tomboly, C.; Ballet, S.; Tourwe, D.; Peter, A.; Martinek, T.; Chung, N. N.; Schiller, P. W.; Benyhe, S.; Borsodi, A., J. Med. Chem. 2007, 50, 328-333.

Characterization of a New Thermophilic Spore Photoproduct Lyase from Geobacillus stearothermophilus (SplG) with Defined Lesion Containing DNA Substrates

Friday 24/11/2006

J. C. Pieck, U. Hennecke, A. J. Pierik, M. G. Friedel, T. Carell, J. Biol. Chem. 2006, 281, 36317-36326.

Natural and Non-Natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus

Thursday 26/10/2006

T. Klar, G. Kaiser, U. Hennecke, T. Carell, A. Batschauer, L.-O. Essen, ChemBioChem 2006, 7, 1798-1806.

Investigation of the Pathways of Excess Electron Transfer in DNA with Flavin-Donor and Oxetane-Acceptor Modified DNA Hairpins

Tuesday 15/08/2006

S. Breeger, M. von Meltzer, U. Hennecke, T. Carell, Chem. Eur. J. 2006, 12, 6469-6477.

Synthesis and evaluation of the beta-turn properties of 4-amino-1,2,4,5-tetrahydro-2-benzazepin-3-ones and of their spirocyclic derivative.

Thursday 08/06/2006

Van Rompaey, K.; Ballet, S.; Tomboly, C.; De Wachter, R.; Vanommeslaeghe, K.; Biesemans, M.; Willem, R.; Tourwe, D., Eur. J. Org. Chem. 2006, 2899-2911.

New 2',6'-dimethyl-L-Tyrosine (Dmt) Opioid Peptidomimetics Based on the Aba-Gly Scaffold. Development of Unique µ-Opioid Receptor Ligands.

Thursday 01/06/2006

Ballet, S.; Salvadori, S.; Trapella, C.; Bryant, S. D.; Jinsmaa, Y.; Lazarus, L. H.; Negri, L.; Giannini, E.; Lattanzi, R.; Tourwe, D.; Balboni, G., J. Med. Chem. 2006, 49, 3990-3993.

Synthesis of substituted 4-amino-2-benzezepin-3-ones via N-acyliminium ion cycliations.

Thursday 18/08/2005

Ballet, S.; Urbanczyk-Lipkowska, Z.; Tourwe, D., Synlett 2005, 2791-2795.

Synthesis and biological evaluation of constrained analogues of the opioid peptide H-Tyr-D-Ala-Phe-Gly-NH2 using 4-amino-2-benzazepin-3-one scaffold.

Saturday 01/01/2005

Ballet, S.; Frycia, A.; Piron, J.; Chung, N.; Schiller, P. W.; Kosson, P.; Lipkowski, A.; Tourwe, D., J. Pept. Res. 2005, 66, 222-230.