Bifunctional opioid/nociceptin hybrid KGNOP1 effectively attenuates pain related behaviour in a rat model of neuropathy.
Starnowska, J.; Guillemyn, K.; Makuch, W.; Mika, J.; Ballet, S.; Przewlocka, B., Eur. J Pharm. 2017, 104, 221-229.
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The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.
Rosado, L. A.; Wahni, K.; Degiacomi, G.; Pedre, B.; Young, D.; de la Rubia, A. G.; Boldrin, F.; Martens, E.; Marcos-Pascual, L.; Sancho-Vaello, E.; Albesa-Jove, D.; Provvedi, R.; Martin, C.; Makarov, V.; Versees, W.; Verniest, G.; Guerin, M. E.; Mateos, L. M.; Manganelli, R.; Messens, J., J. Biol.
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Why DNA is a More Effective Scaffold than RNA in Nucleic Acid-based Asymmetric Catalysis – Supramolecular Control of Cooperative Effects
J. J. Marek, U. Hennecke, Chem. Eur. J. 2017, 23, 6009-6013.
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In Vivo Imaging of the Stability and Sustained Cargo Release of an Injectable Amphipathic Peptide-Based Hydrogel.
Oyen, E.; Martin, C.; Caveliers, V.; Madder, A.; Van Mele, B.; Hoogenboom, R.; Hemot, S.; Ballet, S., Biomacromolecules 2017, 18, 994-1001.
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Bifunctional peptide-based opioid agonist/nociceptin antagonist ligand for dual treatment of nociceptive and neuropathic pain.
Lagard, C.; Chevillard, L.; Guillemyn, K.; Risède, P.; Laplanche, J.-L.; Spetea, M.; Ballet, S.; Mégarbane, B., PAIN 2017, 158, 505-515.
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The Suzuki–Miyaura Cross-Coupling as a Versatile Tool for Peptide Diversification and Cyclization.
Willemse, T.; Schepens, W.; Vlijmen, H.; Maes, B.; Ballet, S., Catalysts 2017, 7, 74.
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Injectable peptide-based hydrogel formulations for the extended in vivo release of opioids.
Martin, C.; Oyen, E.; Van Wanseele, Y.; Ben Haddou, T.; Schmidhammer, H.; Andrade, J.; Waddington, L.; Van Eeckhaut, A.; Van Mele, B.; Gardiner, J.; Hoogenboom, R.; Madder, A.; Spetea, M.; Ballet, S., Materials Today Chemistry 2017, 3, 49-59.
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Hydrazone Linker as a Useful Tool for Preparing Chimeric Peptide/Nonpeptide Bifunctional Compounds.
Dyniewicz, J.; Lipiński, P. F. J.; Kosson, P.; Leśniak, A.; Bochyńska-Czyż, M.; Muchowska, A.; Tourwé, D.; Ballet, S.; Misicka, A.; Lipkowski, A. W., ACS Medicinal Chemistry Letters 2017, 8, 73-77.
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Enantioselective Catalysis using short, structurally-defined DNA Hairpins as Scaffold for Hybrid Catalysts
J. J. Marek, R. Singh, A. Heuer, U. Hennecke, Chem. Eur. J. 2017, 23, 6004-6008.
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Synthesis of Chiral Heterocyclic N-Haloamides and -imides and their Application as Halogenating Agents and Mechanistic Probes
U. Hennecke, C. H. Müller, C. G. Daniliuc, Eur. J. Org. Chem. 2017, 484-490.
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Side Chain Cyclized Aromatic Amino Acids: Great Tools as Local Constraints in Peptide and Peptidomimetic Design.
Van der Poorten, O.; Knuhtsen, A.; Sejer Pedersen, D.; Ballet, S.; Tourwé, D., J. Med. Chem. 2016, 59, 10865-10890.
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Synthesis of Heterocycle-Bridged Peptidic Macrocycles through 1,3-Diyne Transformations.
Verlinden, S.; Ballet, S.; Verniest, G., Eur. J. Org. Chem. 2016, 2016, 5807-5812.
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