ORGC Receives FWO Project funding to develop inhibitors of a viral protein-protein interaction
On December 13th, the FWO announced the results of this year’s applications for WEAVE Research Projects with various partner countries and regions. ORGC – alongside our partner Dr.
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Another award for ORGC!
At the 15th Australian Peptide Conference 🇦🇺 and 13th International Peptide Symposium! 🌏 in Brisbane, our phenomenal student Debora was honoured with first place in the 13th IPS Poster Award supported by Mimotopes, recognising her outstanding PhD research.
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Structure-Based Design and Synthesis of Stapled 10Panx1 Analogues for Use in Cardiovascular Inflammatory Diseases
Lamouroux, A.; Tournier, M.; Iaculli, D.; Caufriez, A.; Rusiecka, O.M.; Martin, C.; Bes, V.; Carpio, L.E.; Girardin, Y.; Loris, R.; Tabernilla, A.; Molica, F.; Gozalbes, R.; Mayán, M.D.; Vinken, M.; Kwak, B.R.; Ballet, S.; J. Med. Chem. 2023, 66, 18, 13086–13102
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Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions
Braet, H.; Fransen, P.-P.; Chen, Y.; Van Herck, S.; Mariën, R.; Vanhoorne, V.; Ceelen, W.; Madder, A.; Ballet, S.; Hoogenboom, R.; De Geest, B.; Hoorens, A.; Dankers, P.Y.W.; De Smedt, S.C.; Remaut, K.; J. Control Release, 2023, 362, 138-150
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Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction
Maseko, S.B.; Brammerloo, Y.; Van Molle, I.; Sogues, A.; Martin, C.; Gorgulla, C.; Plant, E.; Olivet, J.; Blavier, J.; Ntombela, T.; Delvigne, F.; Arthanari, H.; El Hajj, H.; Bazarbachi, A.; Van Lint, C.; Salehi-Ashtiani, K.; Remaut, H.; Ballet, S.; Volkov, A.N.; Twizere, J-C.; Antiviral Research, 2
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Bypassing the Need for Cell Permeabilization: Nanobody CDR3 Peptide Improves Binding on Living Bacteria
Breine, A.; Van holsbeeck, K.; Martin, C.; Gonzalez, S.; Mannes, M.; Pardon, E.; Steyaert, J.; Remaut, H.; Ballet, S.; Van der Henst, C.; Bioconjugate Chem. 2023, 34, 7, 1234-1243
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Introduction of constrained Trp analogs in RW9 modulates structure and partition in membrane models
Lozada, C.; Simon Gonzalez, S.; Agniel, R.; Hindie, M.; Manciocchi, L.; Mazzanti, L.; Ha-Duong, T.; Federica Santoro, F.; Carotenuto, A.; Ballet, S.; Lubin-Germain, N.; Bioorganic chemistry, 2023, 139, 106731
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Congratulations, Dr. Lozada
On Friday 23rd June, Camille Lozada – a joint PhD student of CY Cergy Paris University and the Vrije Universiteit Brussel – was given the opportunity to defend her PhD thesis entitled “ Alteration of the membranotropic properties of cell-penetrating and fusion peptides by means of conformatio...
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Prof. Ballet laureate of the Evotec Prize for Excellence in Molecular Design
On 19th June 2023, it was announced that Prof. Ballet had been awarded the Evotec Prize for Excellence in Molecular Design, awarded under the auspices of the French Medchem Society (Société de Chimie Thérapeutique, SCT). The prize was awarded for Prof.
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Workshop: Biomaterials
On the 24th of May, ORGC hosted the workshop “Biomaterials” of the FWO Scientific Research Network (FWO WOG) “Supramolecular Chemistry and Materials”. This workshop was organised by UGent, KU Leuven and UHasselt – alongside the VUB – and was attended by 45 participants.
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Determination of structural features that underpin the pannexin1 channel inhibitory activity of the peptide 10Panx1
Caufriez, A.; Lamouroux, A.; Martin, C.; Iaculli, D.; Ergüç, EI.; Gozalbes, R.; Mayan, M.D.; Kwak, B.R.; Tabernilla, A.; Vinken, M.; Ballet, S., Bioorg. Chem. 2023 DOI: 10.1016/j.bioorg.2023.106612
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Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS
Van holsbeeck, K., Fischer, B., Gonzalez, S., Gadais, C., Versées, W., Martins, J. C., Martin, C., Wohlkönig, A., Steyaert, J., Ballet, S., Angew. Chem. Int. Ed. 2023, e202219095; Angew. Chem. 2023, e202219095.
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