Zn-Catalyzed tert-Butyl Nicotinate-Directed Amide Cleavage as a Biomimic of Metallo-Exopeptidase Activity.
Wybon, C. C. D.; Mensch, C.; Hollanders, C.; Gadais, C.; Herrebout, W. A.; Ballet, S.; Maes, B. U. W., ACS Catalysis 2018, 8, 203-218.
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Development of potent and proteolytically stable human neuromedin U receptor agonists.
De Prins, A.; Martin, C.; Van Wanseele, Y.; Skov, L. J.; Tomboly, C.; Tourwe, D.; Caveliers, V.; Van Eeckhaut, A.; Holst, B.; Rosenkilde, M. M.; Smolders, I.; Ballet, S., Eur. J. Med. Chem. 2018, 144, 887-897.
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Efficient One-Pot Access to Trisubstituted 2-Benzazepin-3-ones as Constrained Pseudopeptide Analogues and Privileged Scaffolds.
Van der Poorten, O.; Jida, M.; Tourwé, D.; Ballet, S., Medicinal Chemistry 2018, 14, 400-408.
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Rapid construction of substituted 3-amino-1,5-benzothiazepin-4(5H)-one dipeptide scaffolds through an Ugi-4CR - Ullmann cross-coupling sequence.
Van der Poorten, O.; Van Den Hauwe, R.; Hollanders, K.; Maes, B. U. W.; Tourwe, D.; Jida, M.; Ballet, S., Org. Biomol. Chem. 2018, 16, 1242-1246.
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Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators.
Raaymakers, C.; Verbrugghe, E.; Hernot, S.; Hellebuyck, T.; Betti, C.; Peleman, C.; Claeys, M.; Bert, W.; Caveliers, V.; Ballet, S.; Martel, A.; Pasmans, F.; Roelants, K., Nature Communications 2017, 8, 1495
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χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds.
Van der Poorten, O.; Van Den Hauwe, R.; Eiselt, E.; Betti, C.; Guillemyn, K.; Chung, N. N.; Hallé, F.; Bihel, F.; Schiller, P. W.; Tourwé, D.; Sarret, P.; Gendron, L.; Ballet, S., ACS Medicinal Chemistry Letters 2017, 8, 1177-1182.
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Analgesic Properties of Opioid/NK1 Multitarget Ligands with Distinct in Vitro Profiles in Naive and Chronic Constriction Injury Mice.
Starnowska, J.; Costante, R.; Guillemyn, K.; Popiolek-Barczyk, K.; Chung, N. N.; Lemieux, C.; Keresztes, A.; Van Duppen, J.; Mollica, A.; Streicher, J.; Vanden Broeck, J.; Schiller, P. W.; Tourwé, D.; Mika, J.; Ballet, S.; Przewlocka, B., ACS Chemical Neuroscience 2017, 8, 2315-2324.
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Cyclisation To Form Small, Medium and Large Rings by Use of Catalysed and Uncatalysed Azide–Alkyne Cycloadditions (AACs).
This microreview briefly summarises recent developments in the cyclisation to form small, medium and large rings (five to 30 or more members) by way of both catalysed and uncatalysed azide–alkyne cycloaddition (AAC).
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Rational Design of Nanobody80 Loop Peptidomimetics: Towards Biased beta(2) Adrenergic Receptor Ligands.
Martin, C.; Moors, S. L. C.; Danielsen, M.; Betti, C.; Fabris, C.; Pedersen, D. S.; Pardon, E.; Peyressatre, M.; Feher, K.; Martins, J. C.; Mathiesen, J. M.; Morris, M. C.; Devoogdt, N.; Caveliers, V.; De Proft, F.; Steyaert, J.; Ballet, S., Eur. Chem. J. 2017, 23, 9632-9640.
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Amine Activation: N-Arylamino Acid Amide Synthesis from Isothioureas and Amino Acids.
Yan‐Ping, Z.; Pieter, M.; Sergey, S.; Steven, B.; W., M. B. U., Adv. Synth. Catal. 2017, 359, 2481-2498.
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Chemical Modification and Detoxification of the Pseudomonas aeruginosa Toxin 2-Heptyl-4-hydroxyquinoline N-Oxide by Environmental and Pathogenic Bacteria
S. Thierbach, F. S. Birmes, M. C. Letzel, U. Hennecke, S. Fetzner, ACS Chem. Biol. 2017, 12, 2305-2312.
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Stable Bromiranium Ions with Weakly-Coordinating Counterions as Efficient Electrophilic Brominating Agents
C. Ascheberg, J. Bock, F. Buß, C. Mück-Lichtenfeld, C. G. Daniliuc, K. Bergander, F. Dielmann, U. Hennecke, Chem. Eur. J. 2017, 23, 11578-11586.
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