Developing nanobodies as allosteric molecular chaperones of glucocerebrosidase function
Dal Maso, T.; Sinisgalli, C.; Zilio, G.; Franzin, E.; Tessari, I.; Pardon, E.; Steyaert, J.; Ballet, S.; Greggio, E.; Versées, W.; Plotegher, N.; doi: 10.1038/s41467-025-60134-4.Nature Nat Commun . 2025 May 27;16(1):4890
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Discovery and Characterization of a Selective Inhibitor of Synaptojanin1 5-Phosphatase Activity
Martin, S.; Giakoumakis, D.; Paesmans, J.; Bisi, N.; Drozdzecki A.; Audenaert, D.. Haustraete, J.; Verstreken, P.; Galicia, C.; Ballet, S.; Versées, W. DOI: 10.1021/acsptsci.5c00210 ACS Pub. May 12,2025
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Discovery of bioactive peptides through peptide scanning
Iaculli, D.; Ballet, S.; doi.org/10.1002/psc.70029 Wiley Volume31, Issue6 June 2025 e70029
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A comparative study between phenylglycine and phenylalanine derived peptide hydrogels: Towards atomic elucidation
Bertouille, J.; Van Lommel, R.; Aerts, R.; Dockx, L.; Mangialetto, J.; Van den Brande, N.; Willaert, R.; De Proft, F.; Hennecke, U.; Martin, C.; Herrebout, W.; Jansen, T.; Cunha, A.; Ballet, S., doi.org/10.1016/j.mtchem.2025.102593 SSRN Volume 44, March 2025
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G protein peptidomimetics reveal allosteric effects and stepwise interactions in ghrelin receptor–G protein coupling
Mannes, M.; Martin, C.; Damian, M.; Cantel, S.; Orcel, H.; Fehrentz, JA.; Mouillac, B.; Kniazeff, J.; Banères, JL.; Ballet, S.; DOI: 10.1126/scisignal.ado7692 Pub.Med Sci Signal. 2025 Feb 4;18(872) PMID: 39903809
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Peptide hydrogel-drug conjugates for tailored disease treatment
Cauwenbergh, T.; Ballet, S.; Martin, C.; https://doi.org/10.1016/j.mtbio.2024.101423 Materials Today Bio Volume 31, April 2025, 101423
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Design and synthesis of cyclic lipidated peptides derived from the C-terminus of Cx43 for hemichannel inhibition and cardiac endothelium targeting
Laculli, D.; Montgomery, J.; Lamouroux, A.; Caufriez, A.; Gozalbes, R.; Vinken, M.; Molica, F.; Kwak, B.; Ballet, S.,DOI: 10.1039/d4md00850b RSC Med. Chem. 2025,16, 1289-1303
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The versatility of peptide hydrogels: From self-assembly to drug delivery applications
Heremans, J.; Ballet, S.; Martin, C.,J Pept Sci. 2025 Feb;31(2):e3662. doi: 10.1002/psc.3662. Epub 2024 Nov 19 PMID: 39561971
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Structural basis of μ-opioid receptor targeting by a nanobody antagonist
Yu, J.; Kumar, A.; Zhang, X.; Martin, C.; Van Holsbeeck, K.; Raia, P.; Koehl, A.; Laeremans, T.; Steyaert, J.; Manglik, A.; Ballet, S.; Boland, A.; Stoeber, M.;Nat Commun. 2024 Oct 9;15(1):8687. doi: 10.1038/s41467-024-52947-6. PMID: 39384768 PMCID: PMC11464722
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Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science
Breault, E.; Desgagn, M.; De Neve, J.; Coté, J.; Barlow, T.; Ballet, S.; Sarre, P.; doi.org/10.1016/j.phrs.2024.107408 Pharmacological Research Volume 209, November 2024, 107408
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Fluorinated Peptide Hydrogels Result in Longer In Vivo Residence Time after Subcutaneous Administration
Honfroy, A., Bertouille, J., Turea, A., Cauwenbergh, T., Bridoux, J., Lensen, M., Mangialetto, J., Van den Brande, N., White, J., Gardiner, J., Brigaud, T., Ballet, S., Hernot, S., Chaume, G., Martin, D., Biomacromolecules. 2024 Oct 14;25(10):6666-6680. doi: 10.1021/acs.biomac.4c00872.
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