Design, Synthesis, and In Vitro Characterization of Proteolytically-Stable Opioid-Neurotensin Hybrid Peptidomimetics
De Neve, J., Breault, E., Previti, S., Vangeloven, E., Loranger, B., Chartier, M., Brouillette, R., Lanoie, A., Holleran, BJ., Longpré, JM., Gendron, L., Tourwé, D., Sarret, P., Ballet, S., doi 10.1021/acsptsci.4c00236 pubs.acs.org/ptsci...
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Allosteric nanobodies to study the interactions between SOS1 and RAS
Fischer, B., Uchański, T., Sheryazdanova, A., Gonzalez, S., Volkov, A., Brosens, E., Zögg, T., Kalichuk V., Ballet, S., Versées, W., Sablina, A., Pardon, E., Wohlkönig, A., Steyaert, J., Nat Commun. 2024 Jul 23;15(1):6214.
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Peptide libraries: from epitope mapping to in-depth high-throughput analysis.
Laculli, D., Ballet, S., Sciencedirect Volume 45, Issue 7 , July 2024, Pages 579-582
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Multitarget µ-opioid receptor agonists-neuropeptide FF receptor antagonists induce potent antinociception with reduced adverse side effects.
De Neve, J.; Elhabazi, K.§; Gonzalez, S.; Herby, C.; Schneider, S.; Utard, V.; Fellmann-Clauss, R.; Petit-Demouliere, N.; Lecat, S.; Kremer, M.; Ces, A.; Daubeuf, F.; Martin, C.; Ballet, S.; Bihel, F.; Simonin, F., J Med Chem. 2024 May 9;67(9):7603-7619.
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Paracoccus kondratievae produces poly(3-hydroxybutyrate) under elevated temperature conditions
R. Moanis, H. Geeraert, N. Van den Brande, U. Hennecke, E, Peeters, Environ. Microbiol. Rep. 2024, 16, e13260.
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Internship in CSIRO - Jolien Bertouille
In the context of my PhD research focusing on hydrogels made from self-assembling peptides, I had the chance to undertake a three-month research stay at Australia’s national science agency, CSIRO.
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Peptide Sequence Variations Govern Hydrogel Stiffness: Insights from a Multi-Scale Structural Analysis of H-FQFQFK-NH2 Peptide Derivatives
T. De Maeseneer, T. Cauwenbergh, J. Gardiner, J. F. White, W. Thielemans, C. Martin, P. Moldenaers, S. Ballet, R. Cardinaels, Macromol Biosci. 2024 Mar 29:e2300579.
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Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design
Luis E. Gimenez, C. Martin, J. Yu, C. Hollanders, Ciria C. Hernandez, Y. Wu, D. Yao,G. Won Han, Naima S. Dahir, L. Wu, O. Van der Poorten, A. Lamouroux, M. Mannes, S. Zhao, D. Tourwé, RC. Stevens, RD. Cone, S. Ballet, J. Med. Chem. 2024, 67, 4, 2690–2711
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Sustained release of a human PD-L1 single-domain antibody using peptide-based hydrogels
Heremans, J., Maximilian Awad, R., Bridoux, J., Ertveldt, T., Caveliers V., Madder A., Hoogenboom R., Devoogdt N., Ballet S., Hernot S., Breckpot K., Martin C., Eur J Pharm Biopharm 2024 Mar:196:114183. .
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Vacature technisch expert
Technisch expert - Organische chemie, vakgroepen Chemie en Bio-ingenieurswetenschappen Categorie: Management & Professionals 1 - Werken bij de VUB Ben jij onze Technisch Expert Ingenieur die graag uitkijkt naar e...
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ORGC is Recipient of Innoviris Proof-of-Concept Funding to screen a small-molecule library for application in pancreatic cancer
At the start of November, ORGC became the recipient of Innoviris (Brussels Capital Region) proof-of-concept funding to undertake a high-throughput screening of a commercial small molecule library to discovery lead compounds for further medicinal chemistry work.
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ORGC Receives FWO Project funding to develop G protein Peptidomimetics
On December 13th, the FWO announced the results of this year’s applications for Junior and Senior Research Projects.
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